Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
-activated protein kinase inhibitor on the development of early and long-term injury after renal warm ischaemia 1 1 1 1 1 1,2 C . Jayle ,J.P.Faure , R. Thuillier ,J. M. Goujon ,J.P.Richer and T. Hauet 1 2 ...
Abstract Background. Various types of chemokines/cytokines play important roles in ischaemia /reperfusion injury in kidneys. However, the roles of p38 mitogen‐activated protein kinase (MAPK ...
-activated protein kinase ; CGRPs: G- protein -coupled receptors; RIPreC: remote ischaemic preconditioning; RIPostC: remote ischaemic postconditioning; R: reperfusion; I: ischaemia ; IPreC: ischaemic ...
that PC is an immensely complex process involving multiple signalling systems that are still not fully understood.2As active protein kinase C (PKC) is part of the signalling path that is common to many ...
bovine pulmonary arterial endothelial cells and subjected them to oxygen-glucose deprivation (OGD to simulate ischaemia in vitro. Since protein kinase C (PKC) and ATP-sensitive potassium channels (KATP ...
blocked by the MEK (extracellular signal-regulated kinase (ERK) kinase ) inhibitor (PD98059) but not by sGC or protein kinase C inhibitors. Cotreatment of PD98059 with YC-1 caused a 3.3-, 7.5- and 8.3-fold ...
, dendritic cells, innate immunity, ischaemia reperfusion INTRODUCTION Among the numerous variables that can influence the outcome of the transplanted kidney, an emerging risk factor is represented by ischaemia ...
fibrosis and ultrafiltration failure. We recently demonstrated a crucial role for protein kinase C (PKC) isoform α in mesothelial cells. Methods In this study we investigate the role of PKCβ in PM damage ...
plasticity. The intraneuronal injection of the calcium chelator BAPTA [bis(2‐aminophenoxy)ethane‐N,N,N′,N′‐tetraacetate] and inhibitors of the mitogen‐activated protein kinase pathway blocked both forms ...
of PGE2 can afford protection to the endothelial function against the deleterious effect of ischaemia –reperfusion via an activation of protein kinase C . Acknowledgements This project was supported ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!