Exposure of monocytes to inflammatory or anti-inflammatory conditions also induces predominant differentiation to proinflammatory (M1) or anti-inflammatory (M2) macrophage subsets and phenotype switch between macrophage subsets (Figure). This review characterizes the roles of interferon-regulatory factors in the polarization of non-activated macrophages (M0) to M1 and M2 macrophages.
Immunobiology – Elsevier
Published: Jan 1, 2018
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