An iridovirus-like agent associated with the ‘reddish body syndrome’ (RBS) of farmed turbot Scophthalmus maximus was found in China. By light microscope, many enlarged cells were observed in the spleen and kidney of diseased turbot. Iridovirus-like particles were detected by transmission electron microscopic (TEM) examination in various organs of diseased turbot. The virion had an envelope and viral particles were only present in the cytoplasm of infected cells. TEM images of virions showed them to be icosahedral in symmetry, measuring 120–130 nm from vertex to vertex and 110–116 nm from face to face. Complete virions consisted of three layers: the outer layer was an icosahedral capsid 10–14 nm in thickness, the intermediate layer was an 11–15 nm thick translucent space and the inner spheroid core was a homogeneously electron-dense nucleoid measuring 64–70 nm in diameter. The virus particle acquired an envelope through budding from the cytoplasm into a cytoplasmic vesicle. Infected cells became hypertrophic and the cytoplasm was homogeneous. According to the TEM examination, the virions were mostly in cells of gill, intestinal submucosa, spleen and basement membranes of capillaries in glomeruli of the diseased fish. The spleen was the major target organ for the virus. Further analysis using PCR suggested that the molecular characterization of the virus was different from that of red sea bream iridovirus (RSIV) in Japan, Korea, Taiwan and infectious spleen and kidney necrosis virus (ISKNV) in China. This is the first report of iridovirus infection in turbot in China.
Aquaculture – Elsevier
Published: Jun 14, 2004
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera