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statistically significant (P < 0.05). These results suggest that the amino acids encoded by the cichlid rhodopsin gene have evolved at an accelerated rate by positive selection, at least in several lineages ...
sites are shown in table 3. This analysis was based on backbone position and was relatively insensitive to the bias introduced by using bovine rhodopsin as a model for all taxa. The approach is similar ...
) and α-mannosidase-IIb (α-Man-IIb, CG4606) are required for rhodopsin deglycosylation in Drosophila [11]. The authors further demonstrated that α-Man-II activity is strictly regulated by a phosphatase ...
, like in mammalian visual pigments. A wealth of information from genetics , crystallography, time-resolved spectroscopy and chemical methods have made SRI and the closely related sensory rhodopsin II among ...
is responsible for most of the observed variation in λmax. The ability to study the genetic mechanisms behind phenotypic variation has made opsin a model evolutionary system. In vertebrates, these studies often ...
of plants, fungi, and protists. In this study, we present a broadscale phylogenetic analysis of group II introns using sequence data from both the conserved RNA structure and the intron- encoded reverse ...
- based duplicated genes, the child copy is approximately twice as likely to contain PTCs as the parent copy, whereas young de novo genes are as likely to encode PTCs as DNA- based duplicated new genes ...
. A previous annotation of flatworm GPCRs was based on an early draft of the planarian genome [26]. We found that many GPCR genes are absent from this list, while several genes encode proteins that more closely ...
(numbering based on Fig. 1 alignment), extended TM5 and TM6 helices (compared with bovine rhodopsin , Palczewski et al. 2000), a C-terminus region containing 9 or 10 putative sites of phosphorylation (Table 2 ...
and PIP5K synthesize the same end product, they are not functionally redundant [7] and studies of the mammalian enzymes has defined the molecular basis of substrate specificity [8]. Genes encoding PIP5K ...
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