The objective of this study was to determine the effects of serum-based bioactive proteins on the prevention of squamous gastric ulcer formation in horses in moderate exercise programs over a 21-day period. Horses without ulcers were identified and randomly assigned to treatment or control group. Horses were subjected to a training program which induced squamous gastric ulceration in control horses. In horses treated with 210-g bioactive proteins, the incidence of squamous ulcers was significantly reduced (P = .0001) compared to control horses. In horses treated with 80-g bioactive proteins, 66.67% (10/15) of the control horses developed squamous gastric ulceration compared to 33.55% (5/15) of those administered bioactive proteins. In conclusion, dosing horses with bioactive proteins derived from serum was effective for preventing gastric ulcers in horses experiencing stress from exercise or training.
Journal of Equine Veterinary Science – Elsevier
Published: Aug 1, 2016
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