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tumors per mouse, P < .001, two-sided test). Increased expression of vascular endothelial growth factor in colon tumors vs normal colon was suppressed by loss of PPAR- expression. These findings indicate ...
BackgroundThe prognostic and clinicopathological value of placental -Cadherin (CDH3) in multiple cancers is controversial . The diagnostic significance and functional mechanism of CDH3 in tongue ...
or antitumoral). However, the protumoral effects seem to prevail. Abbreviation: GDF15, growth differentiation factor 15. Figure 2 Open in new tabDownload slide Role of GDF15 in the tumor process. Like the other ...
The Endocrine Factors in Pelvic Tumors , with a Discussion of the Papanicolaou Smear Method for Diagnosis 1 A. E. Rakoff , M.D. 2 Philadelphia, Penna. ↵ 1 Presented at the Thirty-second Annual Meeting ...
The difficulties in defining the exposure of a passive smoker might explain the controversial results regarding an association between passive smoking on one hand and lung cancer, tumors of all sites ...
(VEGF) family of angiogenic growth factors is implicated in the pathophysiology of these complications. We aimed to elucidate the role of these angiogenic factors in placentation and to evaluate ...
therapies or repurpose drugs to optimize placental function and fetal growth , with life-long benefits to human health. hypoxia, hypoxia-inducible factors (HIFs), oxidative stress, reactive oxygen species (ROS ...
Abstract Vascular endothelial growth factor (VEGF), a highly specific mitogen for vascular endothelial cells, is involved in placental vascular growth and remodelling. The aim of this study ...
is a multifunctional cytokine that plays the key role in regulating cell growth and apoptosis [63]. Clues from cancer research implied that TGF-β can act as a switcher between tumor suppression and progression [64 ...
and its role in angiogenesis. VEGF comprises a family of ligands (VEGF-A to -D and placental growth factor [PlGF]) that bind to VEGFR tyrosine kinases [2, 10, 11]. VEGF-A, VEGF-B, and PlGF have decisive ...
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