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. Drosophila CAP is an orthologue of the conserved mammalian CAP protein, an adapter protein of the CAV family ( CAP /Ponsin, ArgBP2 and Vinexin; [39]). The CAV proteins regulate cell adhesion, cytoskeletal ...
and UNR binding sites (Figure 1A, green , hereafter termed ‘region 5’) by (CU)4 de-repressed msl-2 translation (Figure 1B, left panel). To evaluate the contribution of region 5 to regulation mediated by each ...
), into which the cap -binding domain is inserted (16)), intimately contact each other and both domains contribute conserved residues that interact with the capped RNA. The importance of these residues is assessed ...
) antibody is shown in green , and anti-tubulin in magenta. DNA (Hoechst stain) is shown in white. (G) Quantification of anaphase defects shown in (F). Data shown are from a single biological experiment (n>50 ...
in lateral root cap (LRC) cells. Further investigation revealed that genetic variation in the 5’UTR of BnaA3.NIP5;1 dictates the distinct transcript abundance, thus leading to different B efficiency-dependent ...
-galactosidase protein after Tcf21 expression is downregulated was not clear from these studies. However, these data suggest that Tcf21 expressing cells can adopt an SMC phenotype and contribute to the fibrous cap ...
centromere maintenance. One expects to find them conserved across metazoa. Fig. 5. View largeDownload slide — GREEN -associated proteins over evolutionary age and their dN/dS ratio. (A) Bayesian network of CAPs ...
, and chromosome segregation. Condensins are conserved multi-subunit protein complexes that contribute to chromosome organization by regulating chromosome compaction and homolog pairing. Previous work in our ...
with expression patterns and functions divergent from the conserved eIF4E (Rhoads, 2009). Caenorhabditis elegans has four isoforms involved in differentiation between mono- and trimethylated mRNA caps (Keiper et al ...
—an impact that may have more biologically relevant connections to fitness because it is a downstream effect of glucocorticoid function rather than just a measure of release (11 in Fig. 2B). Evidence has been ...
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