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of Alzheimer's disease in late onset families.Science.1993;261:921-923.RMayeuxYSternROttmanThe apolipoprotein epsilon 4 allele in patients with Alzheimer's disease.Ann Neurol.1993;34:752-754 ...
ContextThe apolipoprotein E ( APOE )ϵ 4 allele has been implicated as a significant risk factor in the development of late - onset Alzheimer disease, but the evidence of cognitive sequelae ...
Psychiatry1998651031069667569ESobelJLouhijaRSulkavaZDavanipourKKontulaHMiettinenMTikkanenKKainulainenRTilvisLack of association of apolipoprotein E allele epsilon 4 with late - onset Alzheimer's disease among Finnish ...
, Cognition, Genes, APOE , Social context The APOE e4 allele is a risk factor for late onset Alzheimer’s disease (Cruchaga et al., 2012), as well as for other types of dementia (Kobayashi et al., 2011). However ...
risk of cognitive decline and AD [11–13]. In addition, apolipoprotein E ( APOE ) is a susceptibility gene for AD [14–19]. There is a dose-response relationship between the APOE epsilon 4 (ɛ4) allele ...
;(Folstein, Folstein, & McHugh, 1975)]) to examine their cognitive statuses and ApoE genotypes (125 ApoE ε2/ε3; 610 ApoE ε3/ε3; 139 ApoE ε3/ε4; and 4 ApoE ε4/ε4) using DNA extracted from buccal swab samples ...
with risk-promoting polymorphisms (also present in control populations), any causal effects are likely to be conditional. During its life cycle, the virus binds to many proteins and modifies the expression ...
WorldCat 30. Kulminski A Ukraintseva SV Arbeev KG et al. . Association between APOE epsilon 2/ epsilon 3/ epsilon 4 polymorphism and disability severity in a national long-term care survey sample . Age Ageing ...
of individuals with Alzheimer's disease (AD) are offered testing for the apolipoprotein epsilon 4 ( APOE -ɛ4) genotype, which confers susceptibility to AD. This study has shown minimal psychological impact ...
Flash presentations Thursday, 18 April 2013, 16:30-17:30 31 Systematic screening and repeated lifestyle intervention does not reduce 10 years incidence of cardiovascular disease in the general ...
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