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ABSTRACT Animal models are important in understanding both the pathogenesis of and immunity to tuberculosis (TB). Unfortunately, we are beginning to understand that no animal model perfectly ...
autism, hyperactivity and cerebral palsy. Previously we demonstrated the neuroprotective effect of the KCa3.1 inhibitor TRAM-34, which reduces microglia activation, in the rat model of EOP. In this study ...
revealed a novel signature for reactive HD astrocytes, including a downregulation of NOTCH signaling and fatty acid synthesis genes, and an upregulation of MHC class I and metallothionein genes. Our findings ...
, the molecular factors that mediate early protective versus late detrimental neutrophil effects in the model have been emerging and their discovery holds promise for the identification of novel genetic risk ...
, Jenson AB, Hemming VG, et al. Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin-inactiva ted virus . J Virol 1986 ; 57 : 721 – 8 ...
of neutropenia and rare cases of severe fibrosing alveolitis have been described [1,4,5,10,19,20]. The overall risk of re-activation of latent tuberculosis (LTBI) should be considered before the beginning ...
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