Tetraphenylethylene-based gemini surfactant as nonviral gene delivery system: DNA complexation, gene transfection and cellular tracking

Tetraphenylethylene-based gemini surfactant as nonviral gene delivery system: DNA complexation,... Journal of Photochemistry and Photobiology A: Chemistry 355 (2018) 338–349 Contents lists available at ScienceDirect Journal of Photochemistry and Photobiology A: Chemistry journal home page : www.elsevier.com/locat e/jphotochem Tetraphenylethylene-based gemini surfactant as nonviral gene delivery system: DNA complexation, gene transfection and cellular tracking a,1 a,1 a a a, b, Ke-Xin Zhang , Ai-Xiang Ding , Zheng-Li Tan , You-Di Shi , Zhong-Lin Lu *, Lan He ** Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China National Institute for Food and Drug Control, Institute of Chemical Drug Control, TianTanXiLi 2, Beijing, 100050, China A R T I C L E I N F O A B S T R A C T Article history: Gemini surfactant (GS) has been proved to be a powerful system for nonviral gene delivery. Herein, a Received 4 July 2017 Received in revised form 5 August 2017 family of tetraphenylethylene (TPE)-based GS possessing different lengths of hydrophobic tails and Accepted 8 August 2017 different linkages between the TPE and [12]aneN moieties (1a, 2a, 1b and 2b) were synthesized for Available online 12 August 2017 facilitating DNA condensation, promoting gene transfection and tracing cellular fate of GS/DNA complex. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Photochemistry and Photobiology A: Chemistry Elsevier

Tetraphenylethylene-based gemini surfactant as nonviral gene delivery system: DNA complexation, gene transfection and cellular tracking

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier B.V.
ISSN
1010-6030
eISSN
1873-2666
D.O.I.
10.1016/j.jphotochem.2017.08.020
Publisher site
See Article on Publisher Site

Abstract

Journal of Photochemistry and Photobiology A: Chemistry 355 (2018) 338–349 Contents lists available at ScienceDirect Journal of Photochemistry and Photobiology A: Chemistry journal home page : www.elsevier.com/locat e/jphotochem Tetraphenylethylene-based gemini surfactant as nonviral gene delivery system: DNA complexation, gene transfection and cellular tracking a,1 a,1 a a a, b, Ke-Xin Zhang , Ai-Xiang Ding , Zheng-Li Tan , You-Di Shi , Zhong-Lin Lu *, Lan He ** Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China National Institute for Food and Drug Control, Institute of Chemical Drug Control, TianTanXiLi 2, Beijing, 100050, China A R T I C L E I N F O A B S T R A C T Article history: Gemini surfactant (GS) has been proved to be a powerful system for nonviral gene delivery. Herein, a Received 4 July 2017 Received in revised form 5 August 2017 family of tetraphenylethylene (TPE)-based GS possessing different lengths of hydrophobic tails and Accepted 8 August 2017 different linkages between the TPE and [12]aneN moieties (1a, 2a, 1b and 2b) were synthesized for Available online 12 August 2017 facilitating DNA condensation, promoting gene transfection and tracing cellular fate of GS/DNA complex.

Journal

Journal of Photochemistry and Photobiology A: ChemistryElsevier

Published: Mar 15, 2018

References

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