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oral administrations. Key findings Hydrogel viscosity- dependent sustained drug release profiles were observed with zero-order release kinetics during 8–12 h. In dogs and humans, compared with Pletal ...
considered. We evaluated the RERI metric for the setting of clustered data using both population-averaged and cluster-conditional models . In simulation studies, we found that estimation and inference ...
Abstract Objectives Use of alginate graft copolymers in oral drug delivery reduces dosage form manufacture complexity with reference to mixing or coating processes. It is deemed to give constant ...
of the field work (see Supporting Information). 2 Overall design and rationale This manuscript is organized as a descriptive study protocol that will provide the necessary data for modelling of PPP applications ...
’GGAGTTCAGACGTGTGCTCTTCCGATCTTACHRGGGTATCTAATCC) using 30 amplification cycles with an annealing temperature of 55°C. The amplicon lengths were about 460 bp (the exact length varies depending on the species) and were subjected to sequencing using ...
with acrylic polymers (pH- dependent polymers). The developed delivery system was evaluated in a dextran sulfate (DSS)-induced experimental colitis model for its potential as a new therapeutic approach ...
the somatosensory sense of the mouth. Oral somatosensory cues, such as temperature or touch, always accompany taste and interact with human taste perceptions and gustatory neural activity in animal models . Taste ...
by setting up the biological context underpinning the need for experimental models to study gut bacteria-mucus interactions in the digestive environment. We provide an overview of the structure and function ...
investigated the effect of Sg on colon tumor development using in vitro cultured human colon cancer cells and mouse models of CRC. We demonstrated that Sg promoted colon cancer cell proliferation in a manner ...
, it is poorly understood how comorbidities such as malaria might impact protection afforded by such vaccines. To address this question, we used murine models to investigate whether existing immunity against ...
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