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NUCLEAR MEDICINE AND BIOLOGY Vol. 36, No. 3 CONTENTS April 2009 EDITORIAL William C. Eckelman, Michael R. Kilbourn, Chester A. Mathis Kazunori Kawamura, Tomoteru Yamasaki, Joji Yui, Akiko Hatori, Fujiko Konno, Katsushi Kumata, Toshiaki Irie, Toshimitsu Fukumura, Kazutoshi Suzuki, Iwao Kanno, Ming-Rong Zhang Alicia E. Reid, Jacob Hooker, Elena Shumay, Jean Logan, Colleen Shea, Sung Won Kim, Shanika Collins, Youwen Xu, Nora Volkow, Joanna S. Fowler Zhi Yang, Dimitrios P. Kontoyiannis, Xiaoxia Wen, Chiyi Xiong, Rui Zhang, Nathaniel D. Albert, Chun Li Haixun Guo, Nalini Shenoy, Benjamin M. Gershman, Jianquan Yang, Larry A. Sklar, Yubin Miao Lihui Wei, Yunpeng Ye, Thaddeus J. Wadas, Jason S. Lewis, Michael J. Welch, Samuel Achilefu, Carolyn J. Anderson Melanie Bayer, Zyrafete Kuçi, Edgar Schömig, Dirk Gründemann, Helmut Dittmann, Rupert Handgretinger, Gernot Bruchelt Takeo Urakami, Koichi Sakai, Tomohiro Asai, Dai Fukumoto, Hideo Tsukada, Naoto Oku Ren-Shyan Liu, Ta-Kai Chou, Chih-Hsien Chang, Chun-Yi Wu, Chi-Wei Chang, Tsui-Jung Chang, Shih-Jen Wang, Wuu-Jyh Lin, Hsin-Ell Wang Shunfang Yang, Qianggang Dong, Ming Yao, Meiping Shi, Jianding Ye, Langxiang Zhao, Jianzhong Su, Weiyong Gu, Wenhui Xie, Kankan Wang, Yanzhi Du, Yao Li, Yan Huang Sung Won Kim, Anat Biegon, Zachary E. Katsamanis, Carolin W. Ehrlich, Jacob M. Hooker, Colleen Shea, Lisa Muench, Youwen Xu, Payton King, Pauline Carter, David L. Alexoff, Joanna S. Fowler Azita Monazzam, Pasha Razifar, Susan Ide, Michael Rugaard Jensen, Raymond Josephsson, Carl Blomqvist, Bengt Langström, Mats Bergström OBITUARY Mathew L. Thakur 343 John McAfee, MD (1926–2008), In Memoriam 235 239 Specific to nonspecific binding in radiopharmaceutical studies: it’s not so simple as it seems! In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [11C]gefitinib Evaluation of 6-([18F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain Gamma scintigraphy imaging of murine invasive pulmonary aspergillosis with a 111In-labeled cyclic peptide Metastatic melanoma imaging with an 111In-labeled lactam bridgecyclized α -melanocyte-stimulating hormone peptide 64Cu-Labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity Uptake of mIBG and catecholamines in noradrenaline- and organic cation transporter-expressing cells: potential use of corticosterone for a preferred uptake in neuroblastoma- and pheochromocytoma cells Evaluation of O -[18F]fluoromethyl-D-tyrosine as a radiotracer for tumor imaging with positron emission tomography Biodistribution, pharmacokinetics and PET Imaging of [18F]FMISO, [18F]FDG and [18F]FAc in a sarcoma- and inflammation-bearing mouse model Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by 99m Tc-MDP bone scintigraphy Reinvestigation of the synthesis and evaluation of [N-methyl-11C] vorozole, a radiotracer targeting cytochrome P450 aromatase Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake Nucl. Med. Biol. is Indexed/Abstracted in: App. Health Phy. Abstr., Biosis Data., CAB Inter., Elsevier BIOBASE/Current Awareness in Biological Sciences, Cam. Sci. Abstr., Chem. Abstr. Serv., Curr. Cont. ISI/BIOMED Data., Curr. Cont./Life Sci., Curr. Cont. SCISEARCH Data., EMBASE/Excerpta Medica, Health & Saf. Sci. Abstr., Index Medicus/Medline, Res. Alert, Tox. Abstr. ISSN 0969-8051 NMBIEO 36(3)235–344 363 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nuclear Medicine and Biology Elsevier

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