T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa

T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia... Baseline concentrations of cholecystokinin-8 (CCK-8) and β-endorphin (β-EP) were measured in T-lymphocytes from 33 restricting patients with anorexia nervosa (AN-R), 23 binging/purging patients with anorexia nervosa (AN-BP), and 24 healthy volunteers. CCK-8 basal values were significantly lower and β-EP values significantly higher in AN-R and AN-BP patients than in normal volunteers. Levels of the peptides were measured three more times during a 4-month combined cognitive-behavioral/psychopharmacological treatment (nortriptyline or fluoxetine in AN-R, fluoxetine or amineptine in AN-BP). CCK-8 values fluctuated (nonsignificantly) during each treatment, while β-EP values decreased (to a significant degree only in fluoxetine-treated AN-R patients). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychiatry Research Elsevier

T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa

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Publisher
Elsevier
Copyright
Copyright © 1995 Elsevier Ltd
ISSN
0165-1781
DOI
10.1016/0165-1781(95)02664-9
Publisher site
See Article on Publisher Site

Abstract

Baseline concentrations of cholecystokinin-8 (CCK-8) and β-endorphin (β-EP) were measured in T-lymphocytes from 33 restricting patients with anorexia nervosa (AN-R), 23 binging/purging patients with anorexia nervosa (AN-BP), and 24 healthy volunteers. CCK-8 basal values were significantly lower and β-EP values significantly higher in AN-R and AN-BP patients than in normal volunteers. Levels of the peptides were measured three more times during a 4-month combined cognitive-behavioral/psychopharmacological treatment (nortriptyline or fluoxetine in AN-R, fluoxetine or amineptine in AN-BP). CCK-8 values fluctuated (nonsignificantly) during each treatment, while β-EP values decreased (to a significant degree only in fluoxetine-treated AN-R patients).

Journal

Psychiatry ResearchElsevier

Published: Nov 29, 1995

References

  • A comparison between the effect of cholecystokinin octapeptide and apomorphine on ingestion of intraorally administered sucrose in male rats
    Bednar, I.; Qureshi, G.A.; Sodersen, P.
  • Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia
    Garner, D.M.; Olmstead, M.P.; Polivy, J.
  • Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia
    Gerner, G.M.; Olmstead, M.P.; Pollidy, J.
  • Perception of hunger and satiety induced by 2-deoxy- D -glucose in anorexia nervosa and bulimia nervosa
    Nakai, Y.; Kinoshita, F.; Koh, T.; Tsujii, S.; Tsukada, T.
  • Effect of standardized test meal on plasma norepinephrine in patients with anorexia nervosa and bulimia
    Pirke, K.M.; Riedel, W.; Tuschl, T.; Schweiger, U.; Schweiger, M.; Spyra, B.

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