Bioorganic & Medicinal Chemistry 26 (2018) 2996–3005 Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry journal homepage: www.elsevier.com/locate/bmc Synthesis and proﬁling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria a,⇑ a a a a,f Paul M. O’ Neill , Paul A. Stocks , Sunil Sabbani , Natalie L. Roberts , Richard K. Amewu , a b c c c Emma R. Shore , Ghaith Aljayyoussi , Iñigo Angulo-Barturén , María Belén , Jiménez-Díaz , c c d b e Santiago Ferrer Bazaga , María Santos Martínez , Brice Campo , Raman Sharma , Susan A. Charman , e e e b a b Eileen Ryan , Gong Chen , David M. Shackleford , Jill Davies , Gemma L. Nixon , Giancarlo A. Biagini , Stephen A. Ward Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Spain Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, P.O. Box 1826, 1215 Geneva, Switzerland Centre for Drug Candidate Optimisation,
Bioorganic & Medicinal Chemistry – Elsevier
Published: Jul 15, 2018
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