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and (all‐ E )‐ retinoic acid . 1,2 This last has selective biological activity for normal growth and epithelial differentiation. Retinoic acid receptors (RARs) have a high affinity both for (all‐ E )‐ retinoic ...
granuiittion, expression of a low amount of high iiffinity. but no low affinity reeeptors (CD 23) for IgE, and a capacity for low-rate histamine synthesis . The differentiation process was charycterlzed ...
. Distinct Mechanisms of Glucose Lowering by Specific Agonists for Peroxisomal Proliferator Activated Receptor □ S and Retinoic Acid X Receptors Received for publication, May 31, 2005, and in revised form ...
calling into question the endogenous occurrence of this compound (Figure 1A7,10,14,17). It seems that 9-cis retinoic acid may be found endogenously only after administration of high doses of synthetic ...
stimulation by retinoic acid 6 (STRA6). In muscle, RBP4 is associated with increased serine 307 phosphorylation of insulin receptor substrate-1, which decreases its affinity to PI3K and promotes IR ...
all-trans- retinoic acid and 9-cis- retinoic acid have been described.In rat breast cancer prevention the 9-cis-isomer is clearly superior to the all-trans-isomer.The 9-cis-isomer has high affinity ...
in mouse embryo mesenchymal progenitor cells [6–8] and vascular cells [9, 10]. Expression is high in the E9.5 embryo, at sites associated with retinoic acid (RA) activity , including in the foregut region ...
retinoic acid : A biologically active metabolite of retinoic acid . Biochemistry 1978;17:4085-4090.Crossref 60. Wald G, Hubbard R: The synthesis of rhodopsin from vitamin A1 . Proc Natl Acad Sci USA 1950;36 ...
to corepressor displacement and recruitment of coactivators promoting active transcription of RAR target genes.19 In untreated stem cells, RAR primary target genes such as Hoxa1, Cyp26a1, and retinoic acid ...
However, the physiologic role of retinoids cannot be extrapolated from these extreme conditions.6 Retinoic acid (RA), the most active derivative of vitamin A, can rescue most defects caused by vitamin ...
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