Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status

Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified... Micro-AbstractThere is a need to identify patients who may benefit from particular treatments. We investigated prognosis in 915 patients with mCRC from 2 phase III trials of panitumumab plus chemotherapy, based on Köhne category and BRAF status. Both Köhne category and BRAF status predicted outcomes in terms of PFS and OS, and panitumumab provided benefits over chemotherapy alone. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Colorectal Cancer Elsevier

Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status

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Publisher
Elsevier
Copyright
Copyright © 2017 The Authors
ISSN
1533-0028
eISSN
1936-0674
D.O.I.
10.1016/j.clcc.2017.09.006
Publisher site
See Article on Publisher Site

Abstract

Micro-AbstractThere is a need to identify patients who may benefit from particular treatments. We investigated prognosis in 915 patients with mCRC from 2 phase III trials of panitumumab plus chemotherapy, based on Köhne category and BRAF status. Both Köhne category and BRAF status predicted outcomes in terms of PFS and OS, and panitumumab provided benefits over chemotherapy alone.

Journal

Clinical Colorectal CancerElsevier

Published: Mar 1, 2018

References

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