Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate

Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated... •Two fCSs with well-repeated units but minor difference in sulfation pattern were investigated.•Both fCS-Ib and fCS-Pg could significantly improve the lipid profile of HFFD mice.•fCS-Pg was more effective in lowering blood TC, LDL and AI levels.•Both fCSs obviously lowered serum glucose and increased hepatic glycogen synthesis.•Both fCSs might be potential antihyperlipdemic drugs with liver protection effect. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Carbohydrate Polymers Elsevier

Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate

Loading next page...
 
/lp/elsevier/sulfation-pattern-of-fucose-branches-affects-the-anti-hyperlipidemic-QeuuWtm9so
Publisher
Elsevier
Copyright
Copyright © 2016 Elsevier Ltd
ISSN
0144-8617
D.O.I.
10.1016/j.carbpol.2016.03.013
Publisher site
See Article on Publisher Site

Abstract

•Two fCSs with well-repeated units but minor difference in sulfation pattern were investigated.•Both fCS-Ib and fCS-Pg could significantly improve the lipid profile of HFFD mice.•fCS-Pg was more effective in lowering blood TC, LDL and AI levels.•Both fCSs obviously lowered serum glucose and increased hepatic glycogen synthesis.•Both fCSs might be potential antihyperlipdemic drugs with liver protection effect.

Journal

Carbohydrate PolymersElsevier

Published: Aug 20, 2016

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off