Carbohydrate Polymers 181 (2018) 1180–1193 Contents lists available at ScienceDirect Carbohydrate Polymers journal homepage: www.elsevier.com/locate/carbpol Review Sugar-based gene delivery systems: Current knowledge and new perspectives a a d b,c a,c, Seo Jin Hong , Min Hye Ahn , Jaiprakash Sangshetti , Pill Hoon Choung , Rohidas B. Arote Department of Molecular Genetics, School of Dentistry, Seoul National University, Seoul, Republic of Korea Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Republic of Korea Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea Y. B. Chavan College of Pharmacy, Dr. Raﬁq Zakaria Campus, Aurangabad, MH State, India ARTICLE I NFO ABSTRACT Keywords: Carbohydrates, one of the most abundant natural compounds and key participants in many biological processes, Drug/Gene delivery are relevant in medical and industrial ﬁelds. In comparison with synthetic polymers, carbohydrates are bio- Polysaccharides compatible and have intrinsic targeting properties, enabling them to interact with cell-surface receptors. Among Nanocarriers the diﬀerent carbohydrates, polysaccharides are naturally occurring biological molecules with tremendous po- Nanomedicine tential for biomedical applications. The physicochemical properties of these polysaccharide based nanoparticles, Transfection eﬃciency such as excellent biocompatibility, surface charge to interact with nucleic acids, low toxicity and
Carbohydrate Polymers – Elsevier
Published: Feb 1, 2018
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