•The prognosis for traumatic brain injury (TBI) patients with subdural hematoma (SDH) remains poor.•Removal of the SDH results in the immediate reversal of ischemia accompanied by an abrupt reduction of mass and an ensuing additional reperfusion injury.•In this review, we describe the epidemiology, pathophysiology and broad clinical background of SDH.•We mention the subdural hematoma rat model. For the successful translation from animal model to real clinical trial, some important points should also be addressed.
Behavioural Brain Research – Elsevier
Published: Mar 15, 2018
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