Stimuli-responsive nanoparticles based on co-assembly of naturally-occurring biomacromolecules for in vitro photodynamic therapy

Stimuli-responsive nanoparticles based on co-assembly of naturally-occurring biomacromolecules... Colloids and Surfaces A 538 (2018) 795–801 Contents lists available at ScienceDirect Colloids and Surfaces A journal homepage: www.elsevier.com/locate/colsurfa Stimuli-responsive nanoparticles based on co-assembly of naturally- occurring biomacromolecules for in vitro photodynamic therapy ⁎⁎ ⁎ ⁎ a,b b a, b b, b, Haifeng Sun , Shukun Li , Wei Qi , Ruirui Xing , Qianli Zou , Xuehai Yan Key Laboratory of Life-Organic Analysis, Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, 57 Jingxuan West Road, Qufu, Shandong 273165, PR China State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, No. 1 North 2nd Street, Zhongguancun, Beijing 100190, PR China GR APHICAL A BSTRACT ARTICLE I NFO ABSTRACT Keywords: Nanomaterials constructed by self-assembly of biomolecules are of particular interest as drug delivery carriers in Polypeptide biomedicine. However, supramolecular construction of nanoparticles by self-assembly of highly hydrophilic Hyaluronic acid biomolecules such as hyaluronic acid still remains a formidable challenge due to their water solubility. Herein, Self-assembly we propose a strategy to fabricate stable nanoparticles by self-assembly of hyaluronic acid without the need of Nanodrugs modification by hydrophobic groups. This strategy involves the electrostatic assembly http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Geoderma Elsevier

Stimuli-responsive nanoparticles based on co-assembly of naturally-occurring biomacromolecules for in vitro photodynamic therapy

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0016-7061
eISSN
1872-6259
D.O.I.
10.1016/j.colsurfa.2017.11.072
Publisher site
See Article on Publisher Site

Abstract

Colloids and Surfaces A 538 (2018) 795–801 Contents lists available at ScienceDirect Colloids and Surfaces A journal homepage: www.elsevier.com/locate/colsurfa Stimuli-responsive nanoparticles based on co-assembly of naturally- occurring biomacromolecules for in vitro photodynamic therapy ⁎⁎ ⁎ ⁎ a,b b a, b b, b, Haifeng Sun , Shukun Li , Wei Qi , Ruirui Xing , Qianli Zou , Xuehai Yan Key Laboratory of Life-Organic Analysis, Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, 57 Jingxuan West Road, Qufu, Shandong 273165, PR China State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, No. 1 North 2nd Street, Zhongguancun, Beijing 100190, PR China GR APHICAL A BSTRACT ARTICLE I NFO ABSTRACT Keywords: Nanomaterials constructed by self-assembly of biomolecules are of particular interest as drug delivery carriers in Polypeptide biomedicine. However, supramolecular construction of nanoparticles by self-assembly of highly hydrophilic Hyaluronic acid biomolecules such as hyaluronic acid still remains a formidable challenge due to their water solubility. Herein, Self-assembly we propose a strategy to fabricate stable nanoparticles by self-assembly of hyaluronic acid without the need of Nanodrugs modification by hydrophobic groups. This strategy involves the electrostatic assembly

Journal

GeodermaElsevier

Published: Feb 15, 2019

References

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