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their correlation with cell fate specification . Motor neuron progenitors (pMN) exhibit a high degree of variability in their Shh responses, which is particularly prominent in the posterior neural tube where the Shh ...
) emerge from a discrete region in the ventral neural tube , rather than from diffuse locations. Marker analysis indicated that OLP development is initiated in the pMN domain of the spinal cord, which also ...
The neural plate is induced during gastrulation when the organizer affects the ectoderm around it. Recent experiments show that axial mesoderm can stimulate formation of specific ventral cell types ...
specification of the neural plate along its anterior–posterior and dorsal– ventral (DV) axes allows the generation of the tremendous variety of neuronal and glial cells that compose the vertebrate central nervous ...
define region- specific neural identity in the neural tube . The surface ectoderm and notochord specify two secondary signalling centres at the ventral and dorsal midlines of the early neural tube ...
in non‐catecholaminergic tissues, including the sensory ganglia, enteric ganglia, and ventral portions of the neural tube during embryonic development. The fate of the transient catecholaminergic cell ...
of diverse cell types in the ventral neural tube . Additionally, Shh also cooperates with Bmp and Fgf molecules in the control of diverse neuronal cell fates in the brain. © 2000 Wiley‐Liss, Inc. INTRODUCTION ...
and that, in the absence of this signal, the caudal-lateral part of the neural plate adopts a medial-like fate . Secondary muscle fate is similarly affected. We conclude that specification of the lateral neural plate ...
differentiation of ventral interneurons at the expense of motoneuron generation. Consequently, the absence of Smad3 expression from the motoneuron progenitor domain during pattern formation of the neural tube ...
Summary: The Nkx‐6.1 homeodomain transcription factor was previously shown to be expressed in ventral neural progenitor cells and subsequently subsets of unidentified motor neurons during early ...
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