Sparking New Frontiers: Using in Vivo Electroporation for Genetic Manipulations

Sparking New Frontiers: Using in Vivo Electroporation for Genetic Manipulations In vivo electroporation is a fascinating new approach by which gene expression, regulation, and function can be studied in developmental systems. This technique offers new opportunities for manipulations in animal models that lack genetic approaches, including avians. Furthermore, this approach is applicable to other embryo populations including mice, ascidians, zebrafish, Xenopus, and Drosophila. In this review, we discuss technical aspects of in vivo electroporation, review recent studies where this approach has been utilized successfully, and identify future directions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Developmental Biology Elsevier

Sparking New Frontiers: Using in Vivo Electroporation for Genetic Manipulations

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Publisher
Elsevier
Copyright
Copyright © 2001 Academic Press
ISSN
0012-1606
eISSN
1095-564X
DOI
10.1006/dbio.2001.0181
Publisher site
See Article on Publisher Site

Abstract

In vivo electroporation is a fascinating new approach by which gene expression, regulation, and function can be studied in developmental systems. This technique offers new opportunities for manipulations in animal models that lack genetic approaches, including avians. Furthermore, this approach is applicable to other embryo populations including mice, ascidians, zebrafish, Xenopus, and Drosophila. In this review, we discuss technical aspects of in vivo electroporation, review recent studies where this approach has been utilized successfully, and identify future directions.

Journal

Developmental BiologyElsevier

Published: May 1, 2001

References

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  • Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration
    Krull, C.E.; Lansford, R.; Gale, N .W.; Collazo, A.; Marcelle, C.; Yancoupoulos, G.D.; Fraser, S.E.; Bronner-Fraser, M.
  • The development of motor projection patterns in the chick hind limb
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