Muscular strength is a modifiable protective factor for mental health across aging populations. Evidence of sex-related differences in its associations with mental health is limited. Therefore, the purpose of this study was to examine sex-related differences in cross-sectional and prospective associations between grip strength and depressive symptoms and status. Participants were community dwelling adults (N = 4505; 56.5% female), aged ≥50 years. As a measure of muscular strength, grip strength (kg) of the dominant hand was assessed using a hand-held dynamometer at baseline. Participants were divided into sex-specific tertiles. The Center for Epidemiological Studies Depression Scale assessed depressive symptoms at baseline and two years later; a score of ≥16 defined caseness of depression. Depressive symptoms were significantly higher among females at baseline (p < 0.001). Prospective models were adjusted for age, sex, waist circumference, social class, smoking, and health status. Among males, the middle and high strength tertiles were non-significantly associated with 32.9% (p = 0.21) and 9.9% (p = 0.74) reduced odds of developing depression, respectively. Among females, the middle and high strength tertiles were non-significantly associated with 28.5% (p = 0.13) and significantly associated with 43.4% (p = 0.01) reduced odds of developing depression, respectively. In the total sample, the middle and high strength tertiles were significantly associated with 31.5% (p = 0.04) and 34.1% (p = 0.02) reduced odds of developing depression, respectively. The interaction between sex and strength was not statistically significant (p = 0.25). The present findings indicated that grip strength was inversely associated with incident depression in older adults, with stronger associations observed among females than males.
Experimental Gerontology – Elsevier
Published: Apr 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera