Self-assembled gelatin-ι-carrageenan encapsulation structures for intestinal-targeted release applications

Self-assembled gelatin-ι-carrageenan encapsulation structures for intestinal-targeted release... Journal of Colloid and Interface Science 517 (2018) 113–123 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Regular Article Self-assembled gelatin-i-carrageenan encapsulation structures for intestinal-targeted release applications Laura G. Gómez-Mascaraque, Beatriz Llavata-Cabrero, Marta Martínez-Sanz, María José Fabra, Amparo López-Rubio Food Safety and Preservation Department, IATA-CSIC, Avda. Agustín Escardino 7, 46980 Paterna, Valencia, Spain graphical a bstract article i nfo abstract Article history: In this work, natural biopolymeric encapsulation structures were developed through the self-assembly of Received 12 December 2017 gelatin and i-carrageenan in aqueous solutions. The interactions of this binary system and of a ternary Revised 29 January 2018 system containing a polyphenol-rich extract were deeply explored for the development of intestinal Accepted 29 January 2018 delivery systems. The processing of the structures (extrusion vs. freeze-drying) greatly influenced release Available online 1 February 2018 properties, explained by the specific interactions between gelatin and polyphenols, thus allowing for tun- ing the processing conditions depending on the desired target application. Release was further controlled Keywords: by incorporating a divalent salt, giving raise to extract-loaded i-carrageenan/gelatin capsules with Coacervation adequate release profiles for intestinal targeted delivery. These results demonstrate the potential of Polyelectrolyte exploiting biopolymer interactions http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Colloid and Interface Science Elsevier

Self-assembled gelatin-ι-carrageenan encapsulation structures for intestinal-targeted release applications

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Inc.
ISSN
0021-9797
eISSN
1095-7103
D.O.I.
10.1016/j.jcis.2018.01.101
Publisher site
See Article on Publisher Site

Abstract

Journal of Colloid and Interface Science 517 (2018) 113–123 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Regular Article Self-assembled gelatin-i-carrageenan encapsulation structures for intestinal-targeted release applications Laura G. Gómez-Mascaraque, Beatriz Llavata-Cabrero, Marta Martínez-Sanz, María José Fabra, Amparo López-Rubio Food Safety and Preservation Department, IATA-CSIC, Avda. Agustín Escardino 7, 46980 Paterna, Valencia, Spain graphical a bstract article i nfo abstract Article history: In this work, natural biopolymeric encapsulation structures were developed through the self-assembly of Received 12 December 2017 gelatin and i-carrageenan in aqueous solutions. The interactions of this binary system and of a ternary Revised 29 January 2018 system containing a polyphenol-rich extract were deeply explored for the development of intestinal Accepted 29 January 2018 delivery systems. The processing of the structures (extrusion vs. freeze-drying) greatly influenced release Available online 1 February 2018 properties, explained by the specific interactions between gelatin and polyphenols, thus allowing for tun- ing the processing conditions depending on the desired target application. Release was further controlled Keywords: by incorporating a divalent salt, giving raise to extract-loaded i-carrageenan/gelatin capsules with Coacervation adequate release profiles for intestinal targeted delivery. These results demonstrate the potential of Polyelectrolyte exploiting biopolymer interactions

Journal

Journal of Colloid and Interface ScienceElsevier

Published: May 1, 2018

References

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