Screening of quorum sensing peptides for biological effects in neuronal cells

Screening of quorum sensing peptides for biological effects in neuronal cells •Quorum sensing peptides were screened to investigate effects on neuronal cells.•Twenty-two peptides showed effects on different neuronal cell types.•Effects are seen on viability, morphology, differentiation and pro-inflammatory markers.•Majority of these active peptides originate from bacilli species.•Our findings may explain the role of microbiome in neuropsychiatric disorders. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Peptides Elsevier

Screening of quorum sensing peptides for biological effects in neuronal cells

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Inc.
ISSN
0196-9781
D.O.I.
10.1016/j.peptides.2018.01.013
Publisher site
See Article on Publisher Site

Abstract

•Quorum sensing peptides were screened to investigate effects on neuronal cells.•Twenty-two peptides showed effects on different neuronal cell types.•Effects are seen on viability, morphology, differentiation and pro-inflammatory markers.•Majority of these active peptides originate from bacilli species.•Our findings may explain the role of microbiome in neuropsychiatric disorders.

Journal

PeptidesElsevier

Published: Mar 1, 2018

References

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