The role of cytology as a diagnostic tool in veterinary medicine is constantly developing and expanding. Over the last 10 to 20 years, it has become established as a reliable method of obtaining a tissue diagnosis in a minimally invasive way. As clinicians have increased their use of this diagnostic methodology and cytopathologists have become more experienced with a wider variety of lesions, the variety of tissues sampled, spectrum of disease processes identified by cytology, and reliability and precision of the diagnoses have increased. The widespread availability of ultrasonography has greatly enhanced the ability to accurately sample focal lesions deep within body cavities. Cytology and histopathology remain complementary diagnostic procedures, reflecting a trade-off between the lower degree of invasiveness of sample collection with cytology and the increased amount of information available from the ability to evaluate tissue architecture with histopathology. Other than the experience of the cytopathologist evaluating the samples, one of the major factors determining the diagnostic value of cytologic specimens is the quality of the sample. The diagnostic yield of cytology is noticeably higher in the hands of clinicians who have a great deal of experience with obtaining cytologic specimens. With histologic specimens, once the tissue
Veterinary Clinics of North America: Small Animal Practice – Elsevier
Published: Nov 1, 2002
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