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were performed to measure bone parameters. Results Ca2+ transporters in duodenum (TRPV6, calbindin - D9K , PMCA1b) and kidney (TRPV5, calbindin - D28K , NCX1) showed significantly reduced mRNA expression ...
, Tobin AJ 1988 Molecular cloning of mammalian 28,000 Mr vitamin D -dependent calcium binding protein ( calbindin - D28K ): expression of calbindin - D28K RNAs in rodent brain and kidney. DNA 7 : 585 – 593 Google ...
, et al. Transgenic analysis of the response of the rat calbindin ‐ D9k gene to vitamin D . Endocrinology 2000; 141: 2301–2308 Google Scholar 37 Glendenning P, Ratajczak T, Dick IM, Prince RL. Calcitriol ...
) on RNA (a) and protein expression (b) of vitamin D receptor (VDR), the epithelial calcium channels transient receptor potential vanilloid type 6 (TRPV6), calbindin - D9K (CaBP-9k), and plasma membrane Ca ...
to increase the release of PTH to restore calcium balance by exerting direct effects on the kidney and bone [2]. The inter- relationship of vitamin D and klotho is a complex process. Administration of 1,25-(OH ...
are provided by calbindin D28K and Na+/Ca2+ exchanger, NCX1. Joost Hoenderop's group in the Netherlands has shown decreased mRNA expression of TRPV6, calbindin D9K , and PMCA1b in the duodenal mucosa of TNFΔARE ...
the mRNA expression of TRPV5 and TRPV6 in the kidneys 2.2 and 3.7-fold, respectively, 24h after the induction of sepsis. Calbindin - D28K mRNA abundance was decreased to about 30% of control levels in response ...
. Calbindin - D28k mRNA and protein expression was up-regulated by 1,25D and also by any dose of 25D. In duodenum, 1,25D produced a 4-5 fold increase in TRPV6 mRNA levels and 25D increased TRPV6 levels between ...
the normal range. Calcitriol (1,25-dihydroxyvitamin D3 [1,25(OH)2D3]), the hormonally active form of vitamin D , is the major controlling hormone of calcium absorption in the distal as well as the proximal ...
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