Clinical Immunology 188 (2018) 81–84 Contents lists available at ScienceDirect Clinical Immunology journal homepage: www.elsevier.com/locate/yclim Reduced frequency of peripheral CD4 + CD45RA + CD31+ cells and autoimmunity phenomena in patients affected by Del22q11 syndrome a, b a a a c Silvia Ricci , Marzio Masini , Claudia Valleriani , Arianna Casini , Martina Cortimiglia , Laura Grisotto , a d a a Clementina Canessa ,GiuseppeIndolﬁ , Francesca Lippi , Chiara Azzari Division of Immunology, Section of Pediatrics, Department of Health Sciences, University of Florence and Anna Meyer Children's Hospital, Florence,Italy Pediatric Division, Sapienza University, Rome, Italy Department of Statistics, Informatics and Applications "G. Parenti", University of Florence, Florence, Italy Pediatric Division, Anna Meyer Children's Hospital, Florence, Italy article i nfo developing severe infections and/or autoimmune manifestations in pa- tients with Del22q11 syndrome . CD4 + CD45RA + CD31+ cells or Article history: recent thymic emigrants (RTEs) are lymphocytes that have only recent- Received 20 October 2017 Received in revised form 22 November 2017 ly left the thymus and have not undergone further proliferation (as doc- accepted with revision 23 December 2017 umented by high TREC concentrations) and antigen selection. Previous Available online 29 December 2017 studies have suggested an
Clinical Immunology – Elsevier
Published: Mar 1, 2018
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