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of randomized trials and real-world evidence. Here, we describe the rationale and design of the PragMeta database which pursues this goal (www.PragMeta.org).MethodsPragMeta is a non-commercial, open data platform ...
GISSI 3 is an open randomized population trial to assess the comparative value of two different therapeutic strategies based on nitrates and angiotensin-converting enzyme inhibition respectively ...
A randomized controlled trial (RCT) is the most definitive tool for evaluation of the effectiveness of an intervention and can establish a cause‐and‐ effect relationship between an intervention ...
the cardioprotective effects of the beta blocker nebivolol in a prospective, placebo-controlled, superiority randomized trial in patients with breast cancer or diffuse large B cell lymphoma (DLBCL) who have a normal ...
. Limited evidence exists from randomized controlled trials supporting the use of interdisciplinary palliative care in the progressive course of HF. The early palliative care in heart failure trial (EPCHF ...
. The secondary objectives are to assess the effects of the treatments vs. placebo on arterial stiffness, lipid profile and C‐reactive protein. The CASHMERE trial is an European randomized study with a 2 × 2 ...
a randomized trial to assess the effectiveness of an electronic alert system for acute kidney injury. With broad inclusion criteria, and a waiver of informed consent, we enroll and randomize virtually every ...
ObjectiveThis manuscript reports on the protocol for a three-arm randomized controlled trial aiming to assess the effect a self-determination theory-based eHealth intervention on physical activity ...
Outlined is the background and rationale for the initiation of a randomized prospective platelet transfusion trial to evaluate the effects of platelet dose on hemostasis and platelet utilization ...
subtended by affected and non-affected coronary vessels, and if this relates to changes in left ventricular function.MethodsThe DAPAHEART trial will be a phase III, single-center, randomized , two-arm ...
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