Rapid, Repeated, and Clustered Loss of Duplicate Genes in Allopolyploid Plant Populations of Independent Origin

Rapid, Repeated, and Clustered Loss of Duplicate Genes in Allopolyploid Plant Populations of... The predictability of evolution is debatable, with recent evidence suggesting that outcomes may be constrained by gene interaction networks ( 1 ). Whole-genome duplication (WGD; polyploidization—ubiquitous in plant evolution ( 2 )) provides the opportunity to evaluate the predictability of genome reduction, a pervasive feature of evolution ( 3, 4 ). Repeated patterns of genome reduction appear to have occurred via duplicated gene (homeolog) loss in divergent species following ancient WGD ( 5–9 ), with evidence for preferential retention of duplicates in certain gene classes ( 8–10 ). The speed at which these patterns arise is unknown. We examined presence/absence of 70 homeologous loci in 59 Tragopogon miscellus plants from five natural populations of independent origin; this allotetraploid arose ∼80 years ago via hybridization between diploid parents and WGD ( 11 ). Genes were repeatedly retained or lost in clusters, and the gene ontology categories of the missing genes correspond to those lost after ancient WGD in the same family (Asteraceae; sunflower family) ( 6 ) and with gene dosage sensitivity ( 8 ). These results provide evidence that the outcomes of WGD are predictable, even in 40 generations, perhaps due to the connectivity of gene products ( 8, 10, 12 ). The high frequency of single-allele losses detected and low frequency of changes fixed within populations provide evidence for ongoing evolution. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Biology Elsevier

Rapid, Repeated, and Clustered Loss of Duplicate Genes in Allopolyploid Plant Populations of Independent Origin

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Publisher
Elsevier
Copyright
Copyright © 2012 Elsevier Ltd
ISSN
0960-9822
D.O.I.
10.1016/j.cub.2011.12.027
Publisher site
See Article on Publisher Site

Abstract

The predictability of evolution is debatable, with recent evidence suggesting that outcomes may be constrained by gene interaction networks ( 1 ). Whole-genome duplication (WGD; polyploidization—ubiquitous in plant evolution ( 2 )) provides the opportunity to evaluate the predictability of genome reduction, a pervasive feature of evolution ( 3, 4 ). Repeated patterns of genome reduction appear to have occurred via duplicated gene (homeolog) loss in divergent species following ancient WGD ( 5–9 ), with evidence for preferential retention of duplicates in certain gene classes ( 8–10 ). The speed at which these patterns arise is unknown. We examined presence/absence of 70 homeologous loci in 59 Tragopogon miscellus plants from five natural populations of independent origin; this allotetraploid arose ∼80 years ago via hybridization between diploid parents and WGD ( 11 ). Genes were repeatedly retained or lost in clusters, and the gene ontology categories of the missing genes correspond to those lost after ancient WGD in the same family (Asteraceae; sunflower family) ( 6 ) and with gene dosage sensitivity ( 8 ). These results provide evidence that the outcomes of WGD are predictable, even in 40 generations, perhaps due to the connectivity of gene products ( 8, 10, 12 ). The high frequency of single-allele losses detected and low frequency of changes fixed within populations provide evidence for ongoing evolution.

Journal

Current BiologyElsevier

Published: Feb 7, 2012

References

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