Loading next page...
/lp/elsevier/rapid-endocrine-disruption-environmental-estrogen-actions-triggered-k0sPzHF116
- Publisher
- Elsevier
- Copyright
- Copyright © 2006 Elsevier Ltd
- ISSN
- 0960-0760
- eISSN
- 1879-1220
- DOI
- 10.1016/j.jsbmb.2006.09.019
- Publisher site
- See Article on Publisher Site
Abstract
An exogenous substance is defined as an endocrine disrupter chemical (EDC) if it alters the function of the endocrine system provoking adverse health effects. Environmental estrogens are the most studied EDCs. They follow the same mechanisms of action as the gonadal hormone 17β-estradiol. Up to now, the estrogenicity of environmental estrogenic pollutants has been based on the property of these compounds to bind to estrogen receptors (ERs), either ERα or ERβ, and to act subsequently as transcription factors when binding to the estrogen response element (ERE) in the DNA. All the estrogenic bioassays currently used are based on this mechanism of action. New evidence indicates that the definition of estrogenicity for a chemical should take into account other estrogen receptors as well as new signaling pathways. These include the activation of additional transcription factors as well as the action of xenoestrogens through estrogen receptors located outside the nucleus: in the plasma membrane, mitochondria and probably the cytosol. Therefore, new estrogenic bioassays should be developed to include the novel concept of rapid endocrine disruption.
Journal
The Journal of Steroid Biochemistry and Molecular Biology – Elsevier
Published: Dec 1, 2006
Recommended Articles
Loading...
References
-
Mechanisms of estrogen actionNilsson, S.; Makela, S.; Treuter, E.; Tujague, M.; Thomsen, J.; Andersson, G.; Enmark, E.; Pettersson, K.; Warner, M.; Gustafsson, J.A.
-
Strengths and weaknesses of in vitro assays for estrogenic and androgenic activitySoto, A.M.; Maffini, M.V.; Schaeberle, C.M.; Sonnenschein, C.
-
New modes of action for endocrine-disrupting chemicalsTabb, M.M.; Blumberg, B.
-
NFAT signaling: choreographing the social lives of cellsCrabtree, G.R.; Olson, E.N.
-
The many faces of CREBCarlezon, W.A.; Duman, R.S.; Nestler, E.J.
-
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cellsThomas, P.; Pang, Y.; Filardo, E.J.; Dong, J.
-
Endocrine disrupters: a human risk?Waring, R.H.; Harris, R.M.
-
Endometrial cell calcium and oestrogen actionPietras, R.J.; Szego, C.M.
-
The effects of microelectrophoretically applied estrogen, cortisol and acetylcholine on medial preoptic-septal unit activity throughout the estrous cycle of the female ratKelly, M.J.; Moss, R.L.; Dudley, C.A.
-
Differential effects of estradiol and estradiol–BSA conjugatesStevis, P.E.; Deecher, D.C.; Suhadolnik, L.; Mallis, L.M.; Frail, D.E.
-
Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunitValverde, M.A.; Rojas, P.; Amigo, J.; Cosmelli, D.; Orio, P.; Bahamonde, M.I.; Mann, G.E.; Vergara, C.; Latorre, R.
-
Nongenomic steroid action: controversies, questions, and answersLosel, R.M.; Falkenstein, E.; Feuring, M.; Schultz, A.; Tillmann, H.C.; Rossol-Haseroth, K.; Wehling, M.
-
Oestradiol rapidly inhibits Ca 2+ signals in ciliary neurons through classical oestrogen receptors in cytoplasmViso-Leon, M.C.; Ripoll, C.; Nadal, A.
-
Characteristics of a nonclassical membrane estrogen receptor in the endocrine pancreasRopero, A.B.; Nadal, A.
-
Rapid insulinotropic effect of 17beta-estradiol via a plasma membrane receptorNadal, A.; Rovira, J.M.; Laribi, O.; Leon-quinto, T.; Andreu, E.; Ripoll, C.; Soria, B.
-
Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor betaNadal, A.; Ropero, A.B.; Laribi, O.; Maillet, M.; Fuentes, E.; Soria, B.
-
A nonclassical estrogen membrane receptor triggers rapid differential actions in the endocrine pancreasRopero, A.B.; Soria, B.; Nadal, A.
-
Low doses of the endocrine disruptor bisphenol-A and the native hormone 17beta-estradiol rapidly activate transcription factor CREBQuesada, I.; Fuentes, E.; Viso-Leon, M.C.; Soria, B.; Ripoll, C.; Nadal, A.
-
Estradiol modulates acetylcholine-induced Ca 2+ signals in LHRH-releasing GT1-7 cells through a membrane binding siteMorales, A.; Diaz, M.; Ropero, A.B.; Nadal, A.; Alonso, R.
-
Plasma membrane oestrogen receptor mediates neuroprotection against beta-amyloid toxicity through activation of Raf-1/MEK/ERK cascade in septal-derived cholinergic SN56 cellsGuerra, B.; Diaz, M.; Alonso, R.; Marin, R.
-
Quantitative measurement of estrogen-induced ERK-1 and 2 activation via multiple membrane-initiated signaling pathwaysBulayeva, N.N.; Gametchu, B.; Watson, C.S.
-
The plasma membrane estrogen receptor: nuclear or unclear?Nadal, A.; Ropero, A.B.; Fuentes, E.; Soria, B.
-
Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand bindingPappas, T.C.; Gametchu, B.; Watson, C.S.
-
The other estrogen receptor in the plasma membrane: implications for the actions of environmental estrogens.Watson, C.S.; Pappas, T.C.; Gametchu, B.
-
Xenoestrogen-induced ERK-1 and ERK-2 activation via multiple membrane-initiated signaling pathwaysBulayeva, N.N.; Watson, C.S.
-
Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca 2+ fluxes and prolactin release in GH3/B6 pituitary tumor cellsWozniak, A.L.; Bulayeva, N.N.; Watson, C.S.
-
A transmembrane intracellular estrogen receptor mediates rapid cell signalingRevankar, C.M.; Cimino, D.F.; Sklar, L.A.; Arterburn, J.B.; Prossnitz, E.R.
-
Membrane associated estrogen receptors and related proteins: localization at the plasma membrane and the endoplasmic reticulumGovind, A.P.; Thampan, R.V.
-
The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistanceAlonso-Magdalena, P.; Morimoto, S.; Ripoll, C.; Fuentes, E.; Nadal, A.
-
Low doses of bisphenol A and diethylstilbestrol impair Ca 2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of LangerhansAlonso-Magdalena, P.; Laribi, O.; Ropero, A.B.; Fuentes, E.; Ripoll, C.; Soria, B.; Nadal, A.
-
Rapid, nongenomic responses to ecdysteroids and catecholamines mediated by a novel Drosophila G-protein-coupled receptorSrivastava, D.P.; Yu, E.J.; Kennedy, K.; Chatwin, H.; Reale, V.; Hamon, M.; Smith, T.; Evans, P.D.
-
Endocrine disrupting chemical atrazine causes degranulation through Gq/11 protein-coupled neurosteroid receptor in mast cellsMizota, K.; Ueda, H.
-
Novel type of Gq/11 protein-coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL-2H3)Mizota, K.; Yoshida, A.; Uchida, H.; Fujita, R.; Ueda, H.
-
Pathways of endocrine disruption during male sexual differentiation and masculinizationSharpe, R.M.
-
Disruption of rapid, nongenomic steroid actions by environmental chemicals: interference with progestin stimulation of sperm motility in Atlantic croakerThomas, P.; Doughty, K.
-
Effects of estrogens and xenoestrogens on androgen production by Atlantic croaker testes in vitro: evidence for a nongenomic action mediated by an estrogen membrane receptorLoomis, A.K.; Thomas, P.
-
Pesticides interfere with the nongenomic action of a progestogen on meiotic maturation by binding to its plasma membrane receptor on fish oocytesDas, S.; Thomas, P.
-
Effects of estrogenic compounds on human spermatozoa: evidence for interaction with a nongenomic receptor for estrogen on human sperm membraneLuconi, M.; Bonaccorsi, L.; Forti, G.; Baldi, E.
-
Minireview: a plethora of estrogen receptors in the brain: where will it end?Toran-Allerand, C.D.
-
Oestrogen as a neuroprotective hormoneBehl, C.
-
Why females live longer than males: control of longevity by sex hormonesVina, J.; Borras, C.; Gambini, J.; Sastre, J.; Pallardo, F.V.
-
Differential cellular localization of estrogen receptor alpha in uterine and mammary cellsMonje, P.; Zanello, S.; Holick, M.; Boland, R.
-
Subcellular distribution of native estrogen receptor alpha and beta isoforms in rabbit uterus and ovaryMonje, P.; Boland, R.
-
Mitochondrial localization of ERalpha and ERbeta in human MCF7 cellsChen, J.Q.; Delannoy, M.; Cooke, C.; Yager, J.D.
-
Mitochondrial localization of estrogen receptor betaYang, S.H.; Liu, R.; Perez, E.J.; Wen, Y.; Stevens, S.M.; Valencia, T.; Brun-Zinkernagel, A.M.; Prokai, L.; Will, Y.; Dykens, J.; Koulen, P.; Simpkins, J.W.
-
Functional estrogen receptors in the mitochondria of breast cancer cellsPedram, A.; Razandi, M.; Wallace, D.C.; Levin, E.R.
-
False positives in MALDI-TOF detection of ERbeta in mitochondriaSchwend, T.; Gustafsson, J.A.
-
Diethylstilbestrol. A novel F0-directed probe of the mitochondrial proton ATPaseMcEnery, M.W.; Pedersen, P.L.
-
F0 “proton channel” of rat liver mitochondria. Rapid purification of a functional complex and a study of its interaction with the unique probe diethylstilbestrolMcEnery, M.W.; Hullihen, J.; Pedersen, P.L.
-
Inhibition of mitochondrial proton F0F1-ATPase/ATP synthase by polyphenolic phytochemicalsZheng, J.; Ramirez, V.D.
-
Purification and identification of an estrogen binding protein from rat brain: oligomycin sensitivity-conferring protein (OSCP), a subunit of mitochondrial F0F1-ATP synthase/ATPaseZheng, J.; Ramirez, V.D.
-
Rapid inhibition of rat brain mitochondrial proton F0F1-ATPase activity by estrogens: comparison with Na + , K + -ATPase of porcine cortexZheng, J.; Ramirez, V.D.
-
Modulation of mitochondrial Ca(2+) uptake by estrogen receptor agonists and antagonistsLobaton, C.D.; Vay, L.; Hernandez-Sanmiguel, E.; Santodomingo, J.; Moreno, A.; Montero, M.; Alvarez, J.
-
Direct activation of the mitochondrial calcium uniporter by natural plant flavonoidsMontero, M.; Lobaton, C.D.; Hernandez-Sanmiguel, E.; Santodomingo, J.; Vay, L.; Moreno, A.; Alvarez, J.
-
Environmental estrogenic pollutants induce acute vascular relaxation by inhibiting L-type Ca 2+ channels in smooth muscle cellsRuehlmann, D.O.; Steinert, J.R.; Valverde, M.A.; Jacob, R.; Mann, G.E.
-
Estrogen receptor independent rapid non-genomic effects of environmental estrogens on (Ca 2+ ) i in human breast cancer cellsWalsh, D.E.; Dockery, P.; Doolan, C.M.
-
Non-genomic modulation of dopamine release by bisphenol-A in PC12 cellsYoneda, T.; Hiroi, T.; Osada, M.; Asada, A.; Funae, Y.
-
The environmental estrogen bisphenol A inhibits estradiol-induced hippocampal synaptogenesisMacLusky, N.J.; Hajszan, T.; Leranth, C.
-
Modulation by estrogens and xenoestrogens of recombinant human neuronal nicotinic receptorsNakazawa, K.; Ohno, Y.
-
Effects of PCB congeners on the immune function of Mytilus hemocytes: alterations of tyrosine kinase-mediated cell signalingCanesi, L.; Ciacci, C.; Betti, M.; Scarpato, A.; Citterio, B.; Pruzzo, C.; Gallo, G.
-
Environmental estrogens can affect the function of mussel hemocytes through rapid modulation of kinase pathwaysCanesi, L.; Lorusso, L.C.; Ciacci, C.; Betti, M.; Zampini, M.; Gallo, G.
-
Stimulation of catecholamine synthesis by environmental estrogenic pollutantsYanagihara, N.; Toyohira, Y.; Ueno, S.; Tsutsui, M.; Utsunomiya, K.; Liu, M.; Tanaka, K.
-
Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol AZsarnovszky, A.; Le, H.H.; Wang, H.S.; Belcher, S.M.
-
Neurosteroid-induced hyperalgesia through a histamine release is inhibited by progesterone and p , p ′-DDE, an endocrine disrupting chemicalUchida, H.; Mizuno, K.; Yoshida, A.; Ueda, H.
@Phil_Robichaud
@deepthiw
@JoseServera