Bioorganic & Medicinal Chemistry Letters 28 (2018) 1143–1148 Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry Letters journal homepage: www.elsevier.com/locate/bmcl Radiosynthesis and biological evaluation of F-labeled 4-anilinoquinazoline derivative ( F-FEA-Erlotinib) as a potential EGFR PET agent a,b b a b b b b Shun Huang , Yanjiang Han , Min Chen , Kongzhen Hu , Yongshuai Qi , Penghui Sun , Men Wang , b b b a a,c a,⇑ a,⇑ Hubing Wu , Guiping Li , Quanshi Wang , Zhiyun Du , Kun Zhang , Suqing Zhao , Xi Zheng Department of Pharmaceutical Engineering, Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, China Nanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China Department of Chemical and Environmental Engineering, Wuyi University, Jiangmen, Guangdong 529020, China article i nfo abstract Article history: Epidermal growth factor receptor (EGFR) has gained signiﬁcant attention as a therapeutic target. Several Received 15 May 2017 EGFR targeting drugs (Geﬁtinib and Erlotinib) have been approved by US Food and Drug Administration Revised 18 August 2017 (FDA) and have received high approval in clinical treatment. Nevertheless, the curative effect of these Accepted 25 August 2017 medicines varied
Bioorganic & Medicinal Chemistry Letters – Elsevier
Published: Apr 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera