Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their... Acta Biomaterialia 71 (2018) 474–485 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Full length article Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization a,e,1 a,1 a b a Agnieszka A. Ksia˛zek , Laura Frese , Petra E. Dijkman , Bart Sanders , Sarah E. Motta , a,c a,d,⇑ Benedikt Weber , Simon P. Hoerstrup Institute for Regenerative Medicine (IREM), University of Zurich, Switzerland Eindhoven University of Technology, Department of Biomedical Engineering, Eindhoven, The Netherlands Zurich Center for Integrative Human Physiology (ZIHP), University of Zürich, Switzerland Wyss Zurich Translational Center, University of Zurich and ETH Zurich, Zurich, Switzerland Small Animals Department, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Switzerland ar ti c l e i nf o ab stra ct Article history: Data on in vitro engineered ‘‘off the shelf” matrices support the concept of endogenous cellular repopu- Received 1 November 2017 lation driving the graft’s remodeling via immune-mediated response. This seems important to further Received in revised form 13 February 2018 accelerate the cell reconstitution and may play a crucial role when mononuclear cells are used. Accepted 22 February 2018 Nevertheless, studies on decellularized xenogeneic grafts showed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Biomaterialia Elsevier

Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Ltd
ISSN
1742-7061
eISSN
1878-7568
D.O.I.
10.1016/j.actbio.2018.02.029
Publisher site
See Article on Publisher Site

Abstract

Acta Biomaterialia 71 (2018) 474–485 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Full length article Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization a,e,1 a,1 a b a Agnieszka A. Ksia˛zek , Laura Frese , Petra E. Dijkman , Bart Sanders , Sarah E. Motta , a,c a,d,⇑ Benedikt Weber , Simon P. Hoerstrup Institute for Regenerative Medicine (IREM), University of Zurich, Switzerland Eindhoven University of Technology, Department of Biomedical Engineering, Eindhoven, The Netherlands Zurich Center for Integrative Human Physiology (ZIHP), University of Zürich, Switzerland Wyss Zurich Translational Center, University of Zurich and ETH Zurich, Zurich, Switzerland Small Animals Department, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Switzerland ar ti c l e i nf o ab stra ct Article history: Data on in vitro engineered ‘‘off the shelf” matrices support the concept of endogenous cellular repopu- Received 1 November 2017 lation driving the graft’s remodeling via immune-mediated response. This seems important to further Received in revised form 13 February 2018 accelerate the cell reconstitution and may play a crucial role when mononuclear cells are used. Accepted 22 February 2018 Nevertheless, studies on decellularized xenogeneic grafts showed

Journal

Acta BiomaterialiaElsevier

Published: Apr 15, 2018

References

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