Acta Biomaterialia 71 (2018) 432–443 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Full length article Protein machineries deﬁning pathways of nanocarrier exocytosis and transcytosis a,b b a,b b c Jonas Reinholz , Christopher Diesler , Susanne Schöttler , Maria Kokkinopoulou , Sandra Ritz , b a,b,⇑ Katharina Landfester , Volker Mailänder Dermatology Clinic, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany Max Planck Institute for Polymer Research (MPIP), Ackermannweg 10, 55128 Mainz, Germany Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz, Germany ar ti c l e i nf o ab stra ct Article history: The transport of nanocarriers through barriers like the gut in a living organism involves the transcytosis Received 18 October 2017 of these nanocarriers through the cell layer dividing two compartments. Understanding how this process Received in revised form 19 February 2018 works is not only essential to further developing strategies for a more effective nanocarrier transport sys- Accepted 3 March 2018 tem but also for providing fundamental insights into the barrier function as a means of protection against Available online 10 March 2018 micro- and nanoplastics in the food chain. We therefore set out to investigate the different uptake
Acta Biomaterialia – Elsevier
Published: Apr 15, 2018
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