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Dry powder inhalers (DPIs) have been proposed as an alternative administration route for protein and peptide drugs. However, DPI particles are easy to aggregate due to the strong interactions between ...
of various drugs because it avoids the heating step during the DPI preparation process. molecules Article Dry Powder Inhalers for Proteins Using Cryo-Milled Electrospun Polyvinyl Alcohol Nanofiber Mats Takaaki ...
Abstract Inhaled peptides and proteins have promise for respiratory and systemic disease treatment. Engineered spray-dried powder formulations have been shown to stabilize peptides and proteins ...
by encapsulation of protein into respirable, biodegradable microcapsules prepared by an oil in oil emulsification/solvent evaporation method. Insulin‐loaded PLGA microcapsules prepared as a dry powder inhaler ...
-34) Prepared as a Dry Powder for Inhalation 1 2 3,4 Sunday A. Shoyele, Neeraj Sivadas, and Sally-Ann Cryan Received 8 June 2010; accepted 29 December 2010; published online 27 January 2011 Abstract ...
Johnson , R. A. ( 1997 ) Preparation of peptide and protein powders for inhalation . Adv. Drug Del. Rev. 26 : 3 – 15 . Google Scholar Crossref Search ADS WorldCat Kerc , J. , Srcic , S., Knez , Z., Sencar ...
of a series of spray-dried protein /sugar powders for inhalation . J. Pharm. Sci. 87 : 1316 – 1321 . Google Scholar Crossref Search ADS PubMed WorldCat Gliniski , J. , Healy , G. C., Platten , J. K. ( 2000 ...
for inhalation therapy of tuberculosis were prepared in one step using a four-fluid nozzle spray drier.[97] These technologies have demonstrated a great potential also in the development of dry powders for protein ...
Abstract Objectives The present study was designed to assess the pharmacokinetic and pharmacodynamic performance of inhaled recombinant human insulin (rh-insulin) dry powders together ...
of biological macromolecules has been explored. Systemic delivery of proteins or peptides via inhalation can be a more patient-friendly and cost-effective alternative to the parenteral route. Peptides / proteins ...
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