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a phasic component of GABA function. However, novel treatments target the tonic component of GABA neurotransmission mediated by benzodiazepine-insensitive GABAAreceptors. Smoking attenuates withdrawal ...
in messenger RNA processing and thereby affect the quantity of the EAAC1 protein.We are currently genotyping additional polymorphisms in the 3′-UTR region to more clearly define the association signal ...
used to control lice [14,15]. They have been proposed to inhibit γ-aminobutyric acid ( GABA )-gated chloride channels, acetylcholinesterase and voltage-gated sodium channels, respectively, leading ...
processed with a double-immunostaining technique that localizes both DA-immunofluorescent (-IF) varicosities and GABA -IF cell bodies show a progressive increase in the interaction of these two neuronal ...
analysis was conducted by omitting each of the individual studies for BDNF levels, without affecting the overall pooled result. Galbraith plot was designed for BDNF levels and gene polymorphism ...
) to define significantly affected pathways, biological processes , molecular interactions, etc. Differences between each treatment group (Poly I:C, MAM and low protein) and control were analyzed individually ...
. Furthermore, they affect the hypothalamic–pituitary–adrenal (HPA) axis and influence neurotransmission implicated in the development of depression, such as noradrenergic, dopaminergic, serotonergic, gamma ...
endoplasmic reticulum processing , impaired synaptic clustering, reduced GABAA receptor function and decreased GABA binding potency. Our study identified GABRA5 as a causative gene for early onset epileptic ...
therapeutic uses for existing, approved drugs—a process thathas value when considering the exorbitant costs of novel drug development. Several computational strategies exist as a way to predict ...
a subcortical function of CRD-NRG1 in the control of body weight. Embryonic onset of CRD-NRG1 in glutamatergic cortical networks resulted in reduced inhibitory neurotransmission and locomotor hyperactivity. Our ...
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