Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor engineering scaffolds

Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor... Acta Biomaterialia 71 (2018) 460–473 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Full length article Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor engineering scaffolds a,⇑,1 b,1 c,⇑ d c a a Wei-Dong Lü , Rui-Fang Sun , Ye-Rong Hu , Jan-Rong Lu ,LuGu , Zhi-Gang Liu , Guang-Yan Lei , a d Zhun Qiang , Lin Cai Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, Affiliated to the Medical College of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China Department of Pathology, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China Department of Pathology, Tumor Hospital of Shaanxi Province, Affiliated to the Medical College of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China ar ti c l e i nf o ab stra ct Article history: Acellular tumor extracellular matrices (ECMs) have limitations when employed as three-dimensional Received 7 November 2017 (3D) scaffolds for tumor engineering. In this work, methylene blue-mediated photooxidation was used Received in revised form 8 February 2018 to crosslink acellular tumor ECMs. Photooxidative crosslinking greatly increased the stiffness of acellular Accepted 8 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Biomaterialia Elsevier

Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor engineering scaffolds

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Publisher
Elsevier
Copyright
Copyright © 2018 Acta Materialia Inc.
ISSN
1742-7061
eISSN
1878-7568
D.O.I.
10.1016/j.actbio.2018.03.020
Publisher site
See Article on Publisher Site

Abstract

Acta Biomaterialia 71 (2018) 460–473 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Full length article Photooxidatively crosslinked acellular tumor extracellular matrices as potential tumor engineering scaffolds a,⇑,1 b,1 c,⇑ d c a a Wei-Dong Lü , Rui-Fang Sun , Ye-Rong Hu , Jan-Rong Lu ,LuGu , Zhi-Gang Liu , Guang-Yan Lei , a d Zhun Qiang , Lin Cai Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, Affiliated to the Medical College of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China Department of Pathology, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China Department of Pathology, Tumor Hospital of Shaanxi Province, Affiliated to the Medical College of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China ar ti c l e i nf o ab stra ct Article history: Acellular tumor extracellular matrices (ECMs) have limitations when employed as three-dimensional Received 7 November 2017 (3D) scaffolds for tumor engineering. In this work, methylene blue-mediated photooxidation was used Received in revised form 8 February 2018 to crosslink acellular tumor ECMs. Photooxidative crosslinking greatly increased the stiffness of acellular Accepted 8

Journal

Acta BiomaterialiaElsevier

Published: Apr 15, 2018

References

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