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Pharmacokinetics of Levetiracetam in Neonates with Seizures

The pharmacokinetics of levetiracetam were determined prospectively in 18 neonates with seizures. Neonates were found to have lower clearance, higher volume of distribution, and a longer half-life as compared with older children and adults. Mild somnolence was the only adverse effect. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Pediatrics Elsevier
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