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the possible use of miRNAs as diagnostic biomarkers in multiple sclerosis (MS). Methods: We performed global miRNA expression profiling analysis in peripheral blood mononuclear cells (PBMCs) and selected miRNAs ...
candidate biomarkers , and the broadening of the treatment arsenal. Recent findings The recent use of genome wide association studies provide new tools for a better understanding of multiple sclerosis etiology ...
for the treatment of multiple sclerosis . However, drug discovery is slowed due to a dearth of biomarkers which can inform target engagement and magnitude and duration of action. Peripheral blood mononuclear cells ...
Background and ObjectivesTo investigate the total circular RNA (circRNA) profile in patients with relapsing-remitting multiple sclerosis (RRMS) and healthy controls (HCs).MethodsHybridization ...
of HAR1A may be a potential molecular biomarker for MS diagnosis; however, no discernible difference was detected in the expression level of HAR1B in the blood samples of MS patients. ...
not available: see fulltext] Inflammation Vol. 45, No. 4, August 2022 ( 2022) https://doi.org/10.1007/s10753-022-01662-9 ORIGINAL ARTICLE Identification of Potential Biomarkers in the Peripheral Blood Mononuclear ...
peripheral blood NfL levels be adopted as a surrogate endpoint in the context of multiple sclerosis clinical trials? The well-established Prentice criteria for defining the necessary attributes of a surrogate ...
as peripheral biomarkers in Parkinson’s disease and progressive supranuclear palsy: a pilot study. Parkinsonism Relat. disease Disord. 93, 77–84 (2021) Breakdown of the blood –brain bar- ...
BackgroundThe increasing number of treatments that are now available to manage patients with multiple sclerosis (MS) highlights the need to develop biomarkers that can be used within the framework ...
disability. In spite of multiple studies in the last two decades, patient inclusion criteria, protocols for peripheral blood stem cell mobilization and bone marrow cell conditioning and methodology of follow ...
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