Pathology of African swine fever: The role of monocyte-macrophage

Pathology of African swine fever: The role of monocyte-macrophage Highlights ► m-MØ show proinflammatory activation, initial cause of course of ASF. ► Viral replication-necrosis of splenic cord MØ: the cause of hyperemic splenomegaly. ► Hemorrhages in acute ASF are caused by phagocytic activation of endothelial cells. ► Subacute ASF: hemorrhages are associated to vasodilatation-increased permeability. ► Lymphopenia and lymphoid depletion is associated to apoptosis in ASF. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Virus Research Elsevier

Pathology of African swine fever: The role of monocyte-macrophage

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Publisher
Elsevier
Copyright
Copyright © 2013 Elsevier B.V.
ISSN
0168-1702
D.O.I.
10.1016/j.virusres.2013.01.017
Publisher site
See Article on Publisher Site

Abstract

Highlights ► m-MØ show proinflammatory activation, initial cause of course of ASF. ► Viral replication-necrosis of splenic cord MØ: the cause of hyperemic splenomegaly. ► Hemorrhages in acute ASF are caused by phagocytic activation of endothelial cells. ► Subacute ASF: hemorrhages are associated to vasodilatation-increased permeability. ► Lymphopenia and lymphoid depletion is associated to apoptosis in ASF.

Journal

Virus ResearchElsevier

Published: Apr 1, 2013

References

  • Intranuclear detection of African swine fever virus DNA in several cell types from formalin-fixed and paraffin-embedded tissues using a new in situ hybridisation protocol
    Ballester, M.; Galindo-Cardiel, I.; Gallardo, C.; Argilaguet, J.M.; Segalés, J.; Rodríguez, J.M.; Rodríguez, F.
  • Apoptosis in porcine macrophages infected in vitro with African swine fever virus (ASFV) strains with different virulence
    Portugal, R.; Leitão, A.; Martins, C.
  • Modulation of immune cell populations and activation markers in the pathogenesis of African swine fever virus infection
    Ramiro-lbáñez, F.; Ortega, A.; Ruiz-Gonzalvo, F.; Escribano, J.M.; Alonso, C.
  • Mesenchymal stromal cells improve renal injury in anti-Thy 1 nephritis by modulating inflammatory cytokines and scatter factors
    Rampino, T.; Gregorini, M.; Bedino, G.; Piotti, G.; Gabanti, E.; Ibatici, A.; Sessarego, N.; Piacenza, C.; Balenzano, C.T.; Esposito, P.; Bosio, F.; Soccio, G.; Frassoni, F.; Dal Canton, A.
  • Hepatic immune response in calves during acute subclinical infection with bovine viral diarrhoea virus type 1
    Risalde, M.A.; Gómez-Villamandos, J.C.; Pedrera, M.; Molina, V.; Cerón, J.J.; Martínez-Subiela, S.; Sánchez-Cordón, P.J.

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