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properties in vitro and in a mouse model of schistosomiasis mansoni. Methods and findings In vitro , phytol reduced the motor activity of worms, caused their death and confocal laser scanning microscopy ...
mouse models, viral-mediated in vivo RNA interference (RNAi) and overexpression, and in vitro NSPC functional assays, we identify H2-Kb as a negative regulator of NSPC proliferation and adult hippocampal ...
” (diNSCs). 1 Open in new tabDownload slide Neurosphere formation from partially reprogrammed fibroblasts. (A): Schematic of the procedure for direct neural induction. Adult mouse fibroblasts were infected ...
by examining BCAM localization in mouse embryos. Immunofluorescent staining of dorsal skin from day 16.5 embryos (E16.5) of wild-type CD1 mice revealed high levels of BCAM throughout the cortex of basal layer ...
inhibit the proliferation of both adult RSCs and their progenitors. This result suggests that active BMP signaling may repress RSC proliferation within the adult mouse CE in vivo. These in vitro anti ...
schistosomula and adult worms and inhibit egg hatching in vitro , were assessed for their efficacy in a mouse model of schistosomiasis using 5 consecutive daily i.v. doses of 2 mg/kg (Rubb12-tri) and 10 mg/kg ...
). Scanning electron microscopy showed the formation of bulges and bubbles throughout the dorsal region of GSK343-treated adult worms. In schistosomula the body was extremely contracted with the presence ...
very active on adult parasites, PZQ has much lower activity against juvenile worms both in vitro and in vivo [5] a fact that can partially explain the low cure rates in high transmission areas where ...
electron micrograph of dorsal surface of adult male S. mansoni recovered from A and B Infected non-treated mice (G2) showing numerous tubercles bearing directed spines (white arrows) and intertubercular ...
of p53 knockdown cells is almost completely reversed with replacement of miR-199a-3p. Also, miR-199a-3p inhibition partially rescues iPS generation impaired by p53. These findings suggest miR-199a-3p ...
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