Micro-AbstractLiquid biopsy, encompassing circulating tumor (ctDNA) and circulating tumor cells, is under investigation to overcome spatial and temporal heterogeneity of metastatic colorectal cancer. Limited comparative data are available. In a cohort of 20 patients, we show that ctDNA was detectable in all cases, whereas circulating tumor cells were detectable in one-third of cases. ctDNA analysis appears readily available to be a candidate for clinical application in metastatic colorectal cancer.
Clinical Colorectal Cancer – Elsevier
Published: Mar 1, 2018
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