Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
evaluated following induction of mitochondrial oxidative stress by N-succinimidyl N-methylcarbamate exposure . In treated cells, perturbation in mitochondrial machinery led to hypermethylation of p16 and smad4 ...
of cardiovascular toxicity induced by PM2.5 that carried the term in vitro. Here, we summarized the suggested mechanisms of PM2.5 leading to adverse effects and cardiovascular toxicity including oxidative stress ...
group included controls. Our results showed higher levels of oxidative mtDNA damage and associated integrated stress response among the exposed individuals. These disturbances were found to be closely ...
), only after ischemia–reperfusion. In the present study, we further observed that DNA hypermethylation of bone morphogenetic protein 4 (Bmp4) promoter in cardiomyocytes caused by prenatal DEX exposure ...
induced DNA damage directly, or oxidative stress -related damage, resulting in cell apoptosis and carcinogenesis in human respiratory system, digestive system, reproductive system, etc. Moreover, BaP ...
DHT treatment induces ERβ suppression, oxidative stress and mitochondria dysfunction in the amygdala with subsequent ALB behavior in male offspring, and AR knockdown partly diminishes this effect ...
and oxidative stress , while rapamycin and umbilical cord-mesenchymal stem cell treatment reversed these abnormalities through de-methylation of the ATG5 gene promoter.ConclusionsImpaired autophagy activity in OSA ...
increased after exposure to TNPs for 24 hours. Furthermore, α-lipoic acid decreased TNP- induced ROS generation and then attenuated TNP-triggered PARP-1 hypermethylation . Meanwhile, 5-aza-2′-deoxycytidine ...
offspring cardiac oxidative stress and DNA hypermethylation , resulting in an epigenetic down-regulation of Sirt1 gene and aberrant development of heart ischemia-sensitive phenotype, which suggests that Sirt 1 ...
Chronic exposure to inducers of DNA base oxidation and single and double strand breaks contribute to tumorigenesis. In addition to the genetic changes caused by this DNA damage, such tumors often ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!