1 Introduction</h5> Zinc (Zn) has been recognized as an essential trace element for the function or structure of more than 300 proteins [1,2] , and is involved in a great number of cellular processes, like DNA synthesis, enzyme activity and cell division [3,4] . It is believed that zinc can stimulate bone formation [5,6] , increase osteogenetic function in osteoblasts through exciting cell proliferation, alkaline phosphatase activity, collagen synthesis and protein synthesis [7–10] . It is also well established that zinc can enhance osteoblast marker gene expressions  .</P>In addition, zinc possesses excellent antibacterial ability [12,13] . Zinc ions are demonstrated to inhibit multiple activities of bacteria, such as transmembrane proton translocation, glycolysis and acid tolerance  . Cummins et al. [15,16] found that many of its antibacterial actions may be caused by the reaction between zinc ions and sulfhydryl groups. Applerot et al.  reported that ZnO exhibits antibacterial effect on both Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) due to a significant enhancement of the oxidative stress.</P>Zinc has thus attracted the interest of implanted materials, and has been incorporated into various kinds of biomaterials [18–20] . Our previous study demonstrated
Colloids and Surfaces B: Biointerfaces – Elsevier
Published: May 1, 2014
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera