Organic extraction of bone lysates improves DNA purification with silica beads

Organic extraction of bone lysates improves DNA purification with silica beads •Crude bone lysates can inhibit DNA purification with paramagnetic silica beads.•Phenol treatment of challenging bone lysates enhances DNA recovery with Maxwell16.•Success of STR-profiling benefits from bone type selection and multiple sampling. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Forensic Science International Elsevier

Organic extraction of bone lysates improves DNA purification with silica beads

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier B.V.
ISSN
0379-0738
D.O.I.
10.1016/j.forsciint.2017.02.003
Publisher site
See Article on Publisher Site

Abstract

•Crude bone lysates can inhibit DNA purification with paramagnetic silica beads.•Phenol treatment of challenging bone lysates enhances DNA recovery with Maxwell16.•Success of STR-profiling benefits from bone type selection and multiple sampling.

Journal

Forensic Science InternationalElsevier

Published: Apr 1, 2017

References

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