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Open-angle glaucoma (OAG) is characterized by optic nerve fiber atrophy and deterioration of the visual field, corresponding to damage to the optic nerve head. Intraocular pressure (IOP) is currently ...
- 1095PubMedGoogle ScholarCrossref 5. Flammer J The vascular concept of glaucoma . Surv Ophthalmol 1994;38 ((suppl)) S3- S6PubMedGoogle ScholarCrossref 6. Flammer JOrgul S Optic nerve blood - flow abnormalities ...
. Efforts at neuroprotection and improvement in blood flow have not yet been shown effective. Symposium Douglas R Anderson Glaucoma is now considered an abnormal physiology in the optic nerve head ...
of the leading causes of blindness are related to abnormalities in retinal blood flow , such as diabetic retinopathy and age-related macular degeneration. In glaucoma , poor circulation in the retina and optic nerve ...
disturbances and basic principles of blood flow regulation. In glaucoma , besides IOP, vascular dysregulation (such as local vasospasm and systemic hypotension, resulting in impaired autoregulation of blood flow ...
Different diseases of the optic disc may be caused by or lead to abnormal vasculature at the optic nerve head. Optical coherence tomography angiography (OCTA) is a novel technology that provides ...
with structural abnormalities and/or functional dysregulation of the vasculature supplying the optic nerve and surrounding retinal tissue. Under normal conditions, blood flow is autoregulated, i.e., maintained ...
demand for blood flow in the glaucomatous areas of the retina. Glaucoma is a multifactorial optic neuropathy, in which both intraocular pressure (IOP) and vascular factors have been suggested ...
Purpose There is increasing evidence that abnormal perfusion of the optic nerve head is an important factor involved in the pathophysiology of glaucoma . Transport and distribution of oxygen ...
, possibly by reducing the blood supply to the optic nerve . Many authors have shown that vascular resistance downstream from the central retinal and posterior ciliary arteries was increased in glaucoma ; using ...
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