•A chemometrically-designed NADES is presented for the first time.•The tailor-made solvent offered excellent skills in terms of phenolic stabilization.•An ultrasound assisted extraction based on NADES prior to HPLC-DAD was developed.•The approach was applied for phenolic determination agro-food industrial by-products.•Extracts can be directly used in pharmaceutical, agricultural and food industries.
Food Chemistry – Elsevier
Published: Jan 15, 2018
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