Homologs of the Notch receptor and its ligands participate in cell fate decisions during vertebrate development. The past year has seen significant advances in knowlege of the role of Notch in Xenopus neuronal development and T-cell development and in our understanding of the Notch signaling pathway in vertebrates. Connections have also been discovered between alterations in Notch function and human disease.
Current Opinion in Genetics & Development – Elsevier
Published: Aug 1, 1997
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