Notch in vertebrates

Notch in vertebrates Homologs of the Notch receptor and its ligands participate in cell fate decisions during vertebrate development. The past year has seen significant advances in knowlege of the role of Notch in Xenopus neuronal development and T-cell development and in our understanding of the Notch signaling pathway in vertebrates. Connections have also been discovered between alterations in Notch function and human disease. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Genetics & Development Elsevier

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Publisher
Elsevier
Copyright
Copyright © 1997 Elsevier Ltd
ISSN
0959-437x
D.O.I.
10.1016/S0959-437X(97)80085-8
Publisher site
See Article on Publisher Site

Abstract

Homologs of the Notch receptor and its ligands participate in cell fate decisions during vertebrate development. The past year has seen significant advances in knowlege of the role of Notch in Xenopus neuronal development and T-cell development and in our understanding of the Notch signaling pathway in vertebrates. Connections have also been discovered between alterations in Notch function and human disease.

Journal

Current Opinion in Genetics & DevelopmentElsevier

Published: Aug 1, 1997

References

  • A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis
    Myat, A; Henrique, D; Ish-Horowicz, D; Lewis, J
  • Expression patterns of jagged, Delta1, Notch1, Notch2 , and Notch3 genes identify ligand-receptor pairs that may function in neural development
    Lindsell, CE; Boulter, J; Disibio, G; Gossler, A; Weinsmaster, G
  • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    Pear, W; Aster, J; Scott, M; Hasserjian, R; Soffer, B; Sklar, J; Baltimore, D

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