NMDA or 5-HT receptor antagonists impair memory reconsolidation and induce various types of amnesia

NMDA or 5-HT receptor antagonists impair memory reconsolidation and induce various types of amnesia •NMDA or serotonin receptor antagonists paired with reminder-induced amnesia.•At an early (1 and 3 days) amnesia phase, the retraining was facilitated.•In the late phase (10 and 30 days), NMDA-dependent amnesia was resistant to retraining.•In the late phase, 5-HT-dependent amnesia retraining caused memory formation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Behavioural Brain Research Elsevier

NMDA or 5-HT receptor antagonists impair memory reconsolidation and induce various types of amnesia

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0166-4328
D.O.I.
10.1016/j.bbr.2018.02.036
Publisher site
See Article on Publisher Site

Abstract

•NMDA or serotonin receptor antagonists paired with reminder-induced amnesia.•At an early (1 and 3 days) amnesia phase, the retraining was facilitated.•In the late phase (10 and 30 days), NMDA-dependent amnesia was resistant to retraining.•In the late phase, 5-HT-dependent amnesia retraining caused memory formation.

Journal

Behavioural Brain ResearchElsevier

Published: Jun 1, 2018

References

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