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High levels of NO generated in the vasculature under inflammatory conditions are usually attributed to inducible nitric - oxide synthase (iNOS), but the role of the constitutively expressed ...
nitric oxide synthase expression and nitrite production . However, modification of the nitric oxide synthesis by drugs in animals and humans appears to be complicated and dependent on numerous factors ...
cells with PD-123319, a type 2 receptor antagonist, prevented the angiotensin II- dependent increase in nitric oxide synthase mRNA, protein levels, and nitric oxide production . In contrast, the type 1 ...
, these findings provide direct evidence to support that disruption of NOS- dependent NO production is associated with salt tolerance in Arabidopsis. Nitric oxide (NO) acts as a signaling molecule with multiple ...
Production of reactive oxygen species caused by dysregulated endothelial nitric - oxide synthase (eNOS) activity is linked to vascular dysfunction. eNOS is a major target protein of the primary ...
- dependent relaxation in isolated pulmonary artery rings. ROC-325 treatment inhibited autophagy and enhanced endothelial nitric oxide synthase activity in lung tissues of monocrotaline-PH rats. In cultured ...
of nitric oxide synthase , as measured by Western blotting. Stimulation of endothelial cell nitric oxide production by thymocytes and splenocytes was inheritable by the specific nitric oxide synthase inhibitor ...
synthesis in T84 cells in a time‐ and dose‐ dependent manner whereas detectable amounts of peroxynitrite were not produced. A novel selective inducible nitric oxide synthase (iNOS) inhibitor 1400 W potently ...
Endothelial cell nitric oxide synthase (NOS) is known to have a N-myristoylation consensus sequence. Such a consensus sequence is not evident in the macrophage, smooth muscle and neuronal NOS ...
▪ Abstract At the interface between the innate and adaptive immune systems lies the high-output isoform of nitric oxide synthase (NOS2 or iNOS). This remarkable molecular machine requires at least 17 ...
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